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KMID : 0359320170570030197
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Korean Journal of Veterinary Research
2017 Volume.57 No. 3 p.197 ~ p.200
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Effects of dietary acetaminophen and vitamin C supplement on serum cortisol and tumor necrosis factor-alpha concentrations in pigs vaccinated with foot-and-mouth disease vaccine
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Cha Chun-Nam
Lee Beom-Jun
Park Eun-Kee
Yoo Chang-Yeol
Kim Suk
Lee Hu-Jang
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Abstract
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This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis factor-α (TNF-α) concentrations in piglets vaccinated with foot-and-mouth disease (FMD) vaccine. Piglets were vaccinated with FMD vaccine and treated with CAV at concentrations of 0.0, 0.5, 1.0, and 2.0 kg/ton feed (P-CON, AD-1, AD-2, and AD-3, groups, respectively) for 5 days post-vaccination. Cortisol and TNF-α levels at 5 days post-treatment in the AD-1?3 groups were significantly lower than that in the P-CON group (p < 0.05). There were no significant differences between AD-2 and AD-3 groups and non-vaccinated, non-CAV-treated piglets.
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KEYWORD
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acetaminophen, cortisol, foot-and-mouse disease vaccination, pigs, tumor necrosis factor-alpha
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